Pharmaceutics, health and cosmetic

The pharmaceutical and cosmetic industries must face new regulations in terms of elemental impurities. It is now essential to be able to specifically and robustly measure the very low levels of metals in active principle or final products. These analyses require real expertise in terms of sample preparation and also performing instrumentation because of often very complex matrices.

Speciation analyses are also useful in this area to better understand the mode of action of some active principles or to identify some impurities present.

The N° 2012-232 decree from the 17th February 2012is a call for the cosmetic industry to declare the use of nanoparticles with a size lower than 100 nm. Our equipment allows us to meet this new regulation with a multiple characterization (size, shape, elements present and size distribution).


Question ? Contact us


  • Development and validation of analytical methods in a Good Manufacturing Practices (GMP)-like quality surrounding
  • Development of speciation methods in active principles and cosmetic products
  • Physic-chemical characterization of nanoparticles
  • Bibliographic studies

Examples of works accomplished

  • Trace element analysis in active principles matching the American and European regulations (USP)
  • Physic-chemical characterization of titanium nanoparticles in sunscreen

  • Validation of an ultrapure water production network to make ophthalmic products
  • Antimony speciation in active principles used for the leichmaniosis treatment
  • Determination of the stability of a Pt-based metallodrug in-vitro and in-vivo

Analytical devices


Routine analytical tools for the total metal content determination

Coupling an elemental analyzer (ICP MS, ICP AES) with a separation technique (HPLC, GC, A4F)

Speciation analysis


Analytical techniques allowing a rapid access to the size, the size distribution and the chemical composition with an excellent sensitivity